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Identification of New Autoantigens by Protein Array Indicates a Role for IL4 Neutralization in Autoimmune Hepatitis
2012
Molecular & Cellular Proteomics
Autoimmune hepatitis (AIH) is an unresolving inflammation of the liver of unknown cause. Diagnosis requires the exclusion of other conditions and the presence of characteristic features such as specific autoantibodies. Presently, these autoantibodies have relatively low sensitivity and specificity and are identified via immunostaining of cells or tissues; therefore, there is a diagnostic need for better and easy-to-assess markers. To identify new AIHspecific autoantigens, we developed a protein
doi:10.1074/mcp.m112.018713
pmid:22997428
pmcid:PMC3518104
fatcat:rq7xexgq7bet3dl6nwu7aifklu