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miR-21 plays a pivotal role in gastric cancer pathogenesis and progression
2008
Laboratory Investigation
Gastric cancer causes nearly one million deaths worldwide per year. Although Helicobacter pylori infection is the main risk factor, in about 80% or more of gastric cancers, the molecular pathway underlying H. pylori infection leading to the development of gastric cancers remains unclear. Recently accumulating evidence suggests that microRNAs (miRNAs) may regulate diverse biological processes and may be important in tumorigenesis. miR-21 has been frequently observed to be aberrantly
doi:10.1038/labinvest.2008.94
pmid:18794849
fatcat:rc6cyzr3lve7dhu2wqms5yuniy