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Author response: Stochastic yield catastrophes and robustness in self-assembly
A guiding principle in self-assembly is that, for high production yield, nucleation of structures must be significantly slower than their growth. However, details of the mechanism that impedes nucleation are broadly considered irrelevant. Here, we analyze self-assembly into finitesized target structures employing mathematical modeling. We investigate two key scenarios to delay nucleation: (i) by introducing a slow activation step for the assembling constituents and, (ii) by decreasing thedoi:10.7554/elife.51020.sa2 fatcat:7cx5fvaxkfheddwqrndz46bdp4