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Enhancing Effect of Trachelogenin from Trachelospermi caulis Extract on Intestinal Barrier Function
Biological and Pharmaceutical Bulletin
Trachelospermi caulis is used widely as an herbal medicine in oriental countries to attenuate fever and pain. We wished to reveal the novel function of this herb and its active component on barrier function in intestinal epithelial cells. Monolayers of intestinal epithelial cells (Caco-2) were used to evaluate the transepithelial electrical resistance (TEER) and quantity of permeated ovalbumin (OVA) as indices of barrier function. T. caulis increased TEER values on cell monolayers and decreaseddoi:10.1248/bpb.b15-00332 pmid:26268064 fatcat:66elkeuv4zhkjcdpraybmzon5m