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In-vitro studies of various carbonyl derivatives on liver alkaline phosphatase
J. Chem. Pharm. Res
The present work describes the effect of semicarbazones, thiosemicarbazones, hydrazones and phenyl hydrazones of simple aryl aldehydes on the activity of liver alkaline phosphatase. The structural moieties under investigation have gained considerable attention in the field of parasitic and infective diseases. These compounds are reported as potent inhibitors of cruzain, falcipain and rhodesain of infecting parasites. We propose that the molecules which possess potential therapeutic activitiesfatcat:m4bx3yxpwbbprcabfbva37ymfy