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Cell Swelling-induced Peptide Hormone Secretion
Cellular Physiology and Biochemistry
Cell volume changes induced in various ways (anisosmotic environment, hormones, oxidative stress, substrate uptake) are an integral part of a signal transduction network regulating cell function. 1, 2, 3 Cell swelling has received increasing attention as a stimulus for a variety of intracellular phenomena. 4 One of the most remarkable effects of cell swelling is its powerful effect in inducing exocytosis of material in intracellular secretory vesicles. Secretion of essentially all so-packageddoi:10.1159/000335849 pmid:22179004 fatcat:65nkzpdqszbktf6s6kwfdkkkhq