Dnase1 Family in Autoimmunity

Minal Engavale, Jon McCord, Britney Mapp, Nadine Nzimulinda, Elisabeth Bengtson, R. Bryan Sutton, Peter A. Keyel
2021 Encyclopedia  
The deoxyribonuclease 1 (Dnase1) family is a key family of endonucleases that degrades DNA. Loss of Dnase1 family function causes several diseases where the host's immune system targets the host, such as systemic lupus erythematosus, hypocomplementemic urticarial vasculitis syndrome.
doi:10.3390/encyclopedia1030044 doaj:1830cadd1b844e6bae933899a7b7f245 fatcat:2wbzktuwvjhyfexc4qmqif6ntm