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eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus
1996
Development
Classical embryological experiments suggest that a posterior signal is required for patterning the developing anteroposterior axis. In this paper, we investigate a potential role for FGF signalling in this process. During normal development, embryonic fibroblast growth factor (eFGF) is expressed in the posterior of the Xenopus embryo. We have previously shown that overexpression of eFGF from the start of gastrulation results in a posteriorised phenotype of reduced head and enlarged proctodaeum.
pmid:9012508
fatcat:2fpzzudslfajtfhszki5qqoyme