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Multigenic diseases are often associated with protein complexes or interactions involved in the same pathway. We wanted to estimate to what extent this is true given a consolidated protein interaction data set. The study stresses data integration and data representation issues. Results: We constructed 497 multigenic disease groups from OMIM and tested for overlaps with interaction and pathway data. A total of 159 disease groups had significant overlaps with protein interaction data consolidateddoi:10.1186/1471-2105-14-47 pmid:23398688 pmcid:PMC3598893 fatcat:setd53qtz5bhrd6rh4plwskygm