The Etiological Consideration of Infantile Spasms
点頭てんかんの病因に関する研究

Soichi KODAMA, Akira SEO, Hirokuni NEGISHI, Hitoshi OGINO, Minoru ISAKA
1973 No to hattatsu = Brain and development  
The children with infantile spasms (West's syndrome) were studied electroencephalographycally and bioc ,hemically. 1) Forty-four percent (8 of 18 cases) of infantile spasms, most of which showed no response to the ACTH-Z treatment, changed into the Lennox syndrome. 2) Tn 8 of 18 cases, the electroencephalographic pattern changed from hypsarhythmia to 2 c/s spike nd wave pattern. 3) The cases of infantile spasms with a history of perinatal injuries were associated with cerebral palsy in high
more » ... entage. 4) The 5-hydroxyindolacetic acid (5-HIAA) level in lumbar cerebrospinal fluids of these patients with Lennox syndrome is low (29-56 ngm/ml) in comparison with that of the other neurological patients (45-82 ngm/m/).
doi:10.11251/ojjscn1969.5.59 fatcat:hjyjubq6tfeolg6n52gfffuq7e