Subcritical water extraction can be used to selectively extraction compounds by varying the temperaturedependent dielectric constant of water. This study investigated subcritical water extraction of decursin and nodakenin yields from Angelica gigas Nakai (AN) quantitatively and qualitatively by HPLC, and HPLC-ESI/MS. Total phenolics, total flavonoid contents, and antioxidant activity were determined by DPPH and ABTS radical scavenging activity, including the effects of varying the extraction

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... ditions of temperature (110- 200 o C) and time (1-20 min) under high pressure (10 MPa). By subcritical water extraction under operating conditions of 120-130 o C, the maximum yields of decursin (6.64±0.42% in the dried material) and nodakenin (3.71±0.28% in the dried material) were obtained. From 190-200 o C the maximum yields of total phenolics (75.97±1.64 mg gallic acid equivalent/g AN), flavonoids (8.56±1.10 mg quercetin equivalent/g AN), DPPH (63.07±1.71%), and ABTS (72.32±2.82%) were obtained.