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The GriPhyN Virtual Data System provides a suite of components and services for data-intensive sciences that enables scientists to systematically and efficiently describe, discover, and share large scale data and computation resources. We describe the design and implementation of such middleware services in terms of a virtual data system interface called Chiron, and present virtual data integration examples from the QuarkNet education project and from functional-MRI-based neuroscience research.doi:10.1002/cpe.968 fatcat:pxtqiiyg6fdohli2hzqkv7ut5a