A 16-year-old Native American male with Navajo familial neurogenic arthropathy presenting with a Charcot joint of his right knee was treated with knee arthrodesis and is reviewed 1 year post surgery. Despite complications including peroneal nerve palsy, knee arthrodesis has restored the ability to ambulate. Both Navajo arthropathy and indications for knee arthrodesis in children are rare. As the Navajo population disperses into the greater community, health professionals should be aware of

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... o familial neurogenic arthropathy and treatment options. Traditional Navajo beliefs require a cautious approach when discussing prognosis and possible adverse outcomes.