SIFTS: Structure Integration with Function, Taxonomy and Sequences resource

Sameer Velankar, José M. Dana, Julius Jacobsen, Glen van Ginkel, Paul J. Gane, Jie Luo, Thomas J. Oldfield, Claire O'Donovan, Maria-Jesus Martin, Gerard J. Kleywegt
2012 Nucleic Acids Research  
The Structure Integration with Function, Taxonomy and Sequences resource (SIFTS; sifts) is a close collaboration between the Protein Data Bank in Europe (PDBe) and UniProt. The two teams have developed a semi-automated process for maintaining up-to-date cross-reference information to UniProt entries, for all protein chains in the PDB entries present in the UniProt database. This process is carried out for every weekly PDB release and the information is stored in the SIFTS
more » ... se. The SIFTS process includes crossreferences to other biological resources such as Pfam, SCOP, CATH, GO, InterPro and the NCBI taxonomy database. The information is exported in XML format, one file for each PDB entry, and is made available by FTP. Many bioinformatics resources use SIFTS data to obtain cross-references between the PDB and other biological databases so as to provide their users with up-to-date information.
doi:10.1093/nar/gks1258 pmid:23203869 pmcid:PMC3531078 fatcat:rnyow6huf5grfp5fz4oyien7zm