Pragati Garg, Ritu Karoli, Simmi Chawla, Nishant Nishant
2016 Journal of Evidence Based Medicine and Healthcare  
PURPOSE To assess the association of thyroid profile with open angle glaucoma. DESIGN Cross-sectional observational study. MATERIAL AND METHOD 128 cases of diagnosed thyroid disorder were enrolled. 5 cases dropped out. Ocular examination included applanation tonometry, stereoscopic optic disc photography, and automated perimetry. Correlative association of thyroid disorder and open angle glaucoma was assessed. RESULTS Of 123 patients of thyroid disorder, 87.8% had hypothyroidism and remaining
more » ... ism and remaining 12.2% had hyperthyroidism. 15.74% of hypothyroidism and 20% of hyperthyroidism patients had open angle glaucoma, which was statistically significant (Pearson chi-square: Value=6.548, df=2, p=0.040). On multivariate analysis with other risk factors like female sex, family history of glaucoma, myopia, hypertension, and diabetes; it was found that hypothyroidism is an independent risk factor for open angle glaucoma. CONCLUSION All patients having thyroid disorder should be investigated for early diagnosis of open angle glaucoma so that if need be antiglaucoma treatment is started at the earliest and the eye maybe saved from any further deterioration.
doi:10.18410/jebmh/2016/707 fatcat:74vxdgfvjvdn7n5xj3mkg6mf74