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Evaluation of NanoLuc substrates for bioluminescence imaging of transferred cells in mice
2021
Journal of Photochemistry and Photobiology. B: Biology
NanoLuc luciferase recently gained popularity due to its small size and superior bioluminescence performance. For in vivo imaging applications, NanoLuc has been limited by its substrate furimazine, which has low solubility and bioavailability. Herein, we compared the performances of recently reported NanoLuc luciferase substrates for in vivo imaging in mice. Two substrates with improved aqueous solubility, hydrofurimazine and fluorofurimazine, were evaluated along with three stabilized
doi:10.1016/j.jphotobiol.2021.112128
pmid:33529963
fatcat:prffaozep5ccrh4a5lobthavhm