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Studies of activated microglia and macrophages in lumbosacral spinal cord following an intraperitoneal injection of 6-aminonicotinamide into adult rats
1993
Histology and Histopathology
The anterior horns of the lumbosacral segment of the spinal cord in rats showed an extensive lesion following an intraperitoneal administration of 6-amino-nicotinamide (6-AN). Neuronal chromatolysis was observed in some of the large efferent neurons 1-7 days after the injection of 6-AN. The capability in their uptake of fluorogold and its retrograde transport was comparable to those in the normal rats. Small neurons presumably internuncial cells underwent degeneration. 8 weeks after 6-AN
pmid:7508304
fatcat:yfbsststlrb5rfo2xbyckshzxu