The MHC I Genotype Influences Early Driver Events in Cancer

2017 Cancer Discovery  
Major finding: Deleting Adrb2, encoding the β2-adrenergic receptor, in tumor endothelial cells suppresses angiogenesis . Mechanism: Adrb2 loss in endothelial cells enhances oxidative phosphorylation to inhibit angiogenesis .
doi:10.1158/2159-8290.cd-rw2017-206 fatcat:ahjy32fw5zcrdk4tfoawtotbuq