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Molecular characterization of CD133+ cancer stem-like cells in endometrial cancer
2013
International Journal of Oncology
A small subset of cells with CD133 expression is thought to have increased chemoresistance and tumorigenicity, features of cancer stem cells (CSCs); the molecular mechanisms by which these properties arise remain unclear. We characterized CD133 + endometrial cancer cells based on microarray analyses of Ishikawa cells. Of the genes upregulated in CD133 + cells compared with CD133cells, we noted several key factors involved in the aggressive behavior of cells, including ABCG2 and matrix
doi:10.3892/ijo.2013.2230
pmid:24366104
fatcat:x4zjieril5d4npx57wpwzlda7q