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Effect of tonsillectomy on specific immune responses for nontypeable Haemophilus influenzae
The effect of tonsillectomy on specific immune responses for nontypeable Haemophilus influenzae was investigated. Tonsil tissues, nasopharyngeal secretions, and epithelial cells of palatine tonsils were obtained and cultured from 32 patients with chronic tonsillitis or tonsillar hypertrophy (mean age, 18; range, 3 to 66) who underwent tonsillectomy. Mononuclear cells were isolated from the tonsils, and the numbers of P6-specific antibody secreting cells were determined by ELISPOT assay. Beforedoi:10.14821/stomatopharyngology1989.11.277 fatcat:3f5jncz33fa5tcxxpbpea7id2q