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Muscle contraction increases lactate transport while reducing sarcolemmal MCT4, but not MCT1
American Journal of Physiology. Endocrinology and Metabolism
Tonouchi, Mio, Hideo Hatta, and Arend Bonen. Muscle contraction increases lactate transport while reducing sarcolemmal MCT4, but not MCT1. Rates of lactate uptake into giant sarcolemmal vesicles were determined in vesicles collected from rat muscles at rest and immediately after 10 min of intense muscle contraction. This contraction period reduced muscle glycogen rapidly by 37-82% in all muscles examined (P Ͻ 0.05) except the soleus muscle (no change P Ͼ 0.05). At an external lactatedoi:10.1152/ajpendo.00358.2001 pmid:11934671 fatcat:awuu5gpxynhqzkbxl2whnpv7qu