Histopathological Studies of Escherichia coli in Albino Mice

Amit Singh, A Upadhyay, P Singh, A Upadhyay
Veterinary Clinical Science   unpublished
Pathogenicity test on 13 isolates out of 35 caused death of mice after intra-peritoneal inoculation. Post mortem analysis revealed gross lesions of enteritis, retentions of urine, necrosis of liver and hemorrhage in lungs. Histopathological analysis showed typical lesions of glomerulonephritis, degeneration of intestinal epithelium, fusion of villi of intestine, liver showing vacular degeneration, congestion, dilatation of hepatic sinusoids and hyperamia. Spleen showed severe haemorrhage and degeneration of parenchymatous tissue.