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Genomic, geographic and temporal distributions of SARS-CoV-2 mutations
The COVID-19 pandemic is the most significant public health issue in recent history. Its causal agent, SARS-CoV-2, has evolved rapidly since its first emergence in December 2019. Mutations in the viral genome have critical impacts on the adaptation of viral strains to the local environment, and may alter the characteristics of viral transmission, disease manifestation, and the efficacy of treatment and vaccination. Using the complete sequences of 1,932 SARS-CoV-2 genomes, we examined thedoi:10.1101/2020.04.22.055863 fatcat:v47fwxfwfrc6hg3o5ngk72mdzi