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A novel class of mannosylated adamantyltripeptides, general formula of which is α-Man-OCH 2 CH(CH 3 )CO-AdGly-L-Ala-D-isoGln, were prepared, characterized, and their possible immunomodulatory properties investigated in some preliminary tests in vivo. All newly synthesized glycopeptides comprise in their structure the adamantylglycyl moiety linked to the dipeptide L-Ala-D-isoGln, as well as mannose. Adjuvant activity of mannosylated adamant-2-yl tripeptides was tested in the mouse model usingdoi:10.5562/cca1827 fatcat:jps7ydladnbezbzjflgawf2fu4