This study aimed to assess the results and effectiveness of using endoscopic vascular staplers for splenic hilar control in 36 consecutive cases who underwent elective laparoscopic splenectomy due to hematologic problems. Materials and Methods: Thirty-six consecutive patients who underwent laparoscopic splenectomy (LS) due to hematologic diseases over a 3-year period between January 2012-May 2015 were included in this study. LS was carried out with the standard 4-port method. All hilar vessels

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... ere divided by using an endoscopic stapler loaded with vascular cartridges. Patient demographic data, hematologic diagnosis, size of the spleen, duration of operation, length of hospital stay, post-operative complications, postoperative analgesic requirement were retrospectively extracted from patient files. Results: A total of 36 consecutive patients were treated in a single center and were operated by two surgeons. There was no conversion to laparotomy or reoperation in the series. One patient developed acute portal vein thrombosis that was medically treated in the early post-operative period. Another patient experienced pneumothorax due to a diaphragmatic injury that was repaired during surgery. The average spleen size was identified as 14.5 cm. An accessory spleen was detected in 5 patients. The mean operative time was 97 minutes, and the mean length of hospital stay was 2.3 days. Conclusion: We believe that using an endoscopic vascular stapler for ligation of hilar vascular structures during elective laparoscopic splenectomy by experienced surgeons is efficient despite the cost disadvantage.