Amyl Nitrite; its Preparation, Purity and Tests

Frank O. Taylor
1914 The Journal of the American Pharmaceutical Association (1912)  
The B. P. says: "A mixture of 5 volumes with sufficient alcohol (90%) to form 100 volumes affords a liquid of which a portion tested in a nitrometer, as described under "Spiritus Aetheris Nitrosi," should yield not less than six times its bulk of nitric oxide gas." This is equivalent to about 66 percent. by weight of pure amyl nitrite. This also is a standard easy of attainment, in fact it is decidedly too low. A sample which will meet the distillation test will more than respond to this assay.
more » ... pond to this assay. Again, the U. S. P. imposes an assay requiring about 80% of pure arnyl nitrite. This is not at all too high but of itself would readily pass a sample as of standard quality which might be far from such. If amyl nitrite has been imperfectly made from an impure alcohol, it might easily contain lower alkyl nitrites and un-
doi:10.1002/jps.3080031023 fatcat:oxq3tt63ynbkfpn5y7w2br2h3y