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Endothelial Network Formation Within Human Tissue-Engineered Skeletal Muscle
2015
Tissue Engineering. Part A
The size of in vitro engineered skeletal muscle tissue is limited due to the lack of a vascular network in vitro. In this paper, we report tissue engineered skeletal muscle consisting of human aligned myofibers with interspersed endothelial networks. We extend our bio-artificial muscle (BAM) model by co-culturing human muscle progenitor cells with human umbilical vein endothelial ce lls (HUVECs) in a fibrin extracellular matrix. First, the optimal medium conditions for co-culturing myoblasts
doi:10.1089/ten.tea.2015.0093
pmid:26177063
pmcid:PMC4605445
fatcat:fqp6c3qs3fh7vgxfaocwz4c2ju