Anticonvulsant monitoring in psychiatric practice

Debbie Nelson, Douglas Gray
2001 Psychiatric bulletin of the Royal College of Psychiatrists  
Aims and Method A Medline literature search revealed a large number of articles on anticonvulsant monitoring. More relevant articles were selected with the aim of summarising current best practice in this area. Results Most articles were written to address monitoring in epilepsy and not psychiatric illness. Serum ranges should only be regarded as guidelines. Some patients may show toxic signs at therapeutic serum levels while others may show tolerance and require higher levels. Clinical
more » ... s. Clinical Implications Appropriate monitoring of serum levels improves efficacy and enhances safety. Clinician ignorance may lead to inappropriate or inaccurate sampling with resultant adverse consequences for the patient.
doi:10.1192/pb.25.9.356 fatcat:c5utofxsijfwvavavdqeq47svm