Gastrointestinal Stromal Tumor Arising in the Pelvic Cavity

Tomonori OHSAWA, Hideyuki ISHIDA, Akio ODAKA, Daijo HASHIMOTO, Masashi FUJIOKA
2004 Nihon Gekakei Rengo Gakkaishi (Journal of Japanese College of Surgeons)  
We herein report an extremely unusual case of gastrointestinal stromal tumor (GIST) arising in a pelvic cavity. A 58-year-old man was admitted complaining of lower abdominal discomfort . Radiological examinations demonstrated a huge lobulated tumor occupying the lower abdominal and pelvic cavity , right hydronephrosis and extramural compression of rectum. Definite preoperative diagnosis was not obtained by transrectal biopsy. En-bloc resection of the tumor was performed by a total pelvic
more » ... ation . Histological examination demonstrated that the tumor was composed of epithelioid cells with a low mitotic index. The tumor cells were immunohistochemically positive for CD-117 (c-kit) but negative for CD34 , asmooth actin, HMB-45, HHF-35, and vimentin. The patient died of heart failure without any evidence of recurrence 15 months postoperatively. To our knowledge, this is the third reported case of GIST arising in the pelvic cavity in the literature throughout the world. The potential occurrence of GIST should be considered in the differential diagnosis of pelvic tumors.
doi:10.4030/jjcs1979.29.4_811 fatcat:7qzf5b4izjgthgrs4w36ckriha