Sentence Reading: A Functional MRI Study at 4 Tesla

D. Bavelier, D. Corina, P. Jezzard, S. Padmanabhan, V. P. Clark, A. Karni, A. Prinster, A. Braun, A. Lalwani, J. P. Rauschecker, R. Turner, H. Neville
1997 Journal of Cognitive Neuroscience  
In this study, changes in blood oxygenation and volume were monitored while monolingual right-handed subjects read English sentences. Our results confirm the role of the left peri-sylvian cortex in language processing. Interestingly, individual subject analyses reveal a pattern of activation characterized by several small, limited patches rather than a few large, anatomically well-circumscribed centers. Between-subject analyses confirm a lateralized pattern of activation and reveal active
more » ... cal language areas including Broca's area, Wernicke's area, and the angular gyms. In addition they point to areas only more recently considered as language-relevant including the anterior portion of the superior temporal sulcus. This area has not been reliably observed in imaging studies of isolated word processing. This raises the hypothesis that activation in this area is dependent on processes specific to sentence reading. 0 preparation phases of this study. We are also grateful to Alexandre Pouget and Karl Friston for inspiring discussions on the analysis techniques and to B. Ewans for her active participation in the taping of the ASL stimuli.
doi:10.1162/jocn.1997.9.5.664 pmid:23965123 fatcat:qw63wjkuunej3gzoeg5nge7x5q