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eNOS se correlaciona com a biogênese mitocondrial em corações com cardiopatia congênita e cianose
2012
Arquivos Brasileiros de Cardiologia
Mitochondrial biogenesis program in heart appears to exhibit adaptive remodeling following biomechanical and oxidative stress. The adaptive mechanisms that protect myocardium metabolism during hypoxia are coordinated in part by nitric oxide (NO). Objective: To observe mitochondrial biogenesis and nitric oxide synthase (NOS) expression in hearts of congenital heart disease with cyanosis, discuss mitochondrial response to chronic hypoxia in myocardium. Methods: 20 patients with cyanotic (n=10) or
doi:10.1590/s0066-782x2012005000072
pmid:22858618
fatcat:bxpnvtldlndjnfltge37xep74q