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Family-Based Analysis of -675 4G/5G Polymorphism in the PAI-1 Gene in Chinese Polycystic Ovary Syndrome
[post]
2021
unpublished
Background: Insulin resistance (IR) is one of the main pathophysiology of PCOS. Previous studies have shown that 4G/5G polymorphism in promoter region of plasminogen activator inhibitor-1 gene(PAI-1) can affect insulin sensitivity by elevating the level and activity of plasma PAI-1, involved in the formation of IR. In order to elucidate the relationship between 4G/5G polymorphism of PAI-1 gene and PCOS, we used transmission disequilibrium test (TDT) to study the nuclear family of PCOS. Purpose:
doi:10.21203/rs.3.rs-382013/v1
fatcat:cefsrzflvfajpo6udiogdmue7e