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Four zona pellucida glycoproteins are expressed in the human
2004
Human Reproduction
The ®rst two authors contributed equally to this work. BACKGROUND: The zona pellucida (ZP) is an extracellular glycoprotein matrix which surrounds all mammalian oocytes. Recent data have shown the presence of four human zona genes (ZP1, ZP2, ZP3 and ZPB). The aim of the study was to determine if all four ZP proteins are expressed and present in the human. METHODS: cDNA derived from human oocytes were used to amplify by PCR the four ZP genes. In addition, isolated native human ZP were
doi:10.1093/humrep/deh301
pmid:15142998
fatcat:frlxs2uyozhsrdukqnq6fgv4ia