P265 Value of CLIA seroconversion with negative RPR and immunoblot for the diagnosis of early syphilis

S Nieuwenburg, P Huurdeman, H de Vries, A van Dam
2021 Poster presentations   unpublished
more MSM, PrEP users and clients notified for or with symptoms of STI were seen during-and post-lockdown compared to pre-lockdown. Chlamydia positivity was around 18% among heterosexual men and 15% among women from 2016-2019, and increased to 21.1% and 16.6% respectively in 2020. Positivity increased during lockdown, up to 32% among heterosexual men, followed by decreases post-lockdown to pre-lockdown levels. Among MSM, the increase during lockdown was smaller, only slightly affecting overall
more » ... sitivity in 2020. Gonorrhoea positivity also increased during lockdown, causing further increasing trends among heterosexuals from 1.8% in 2011 to 2.2% in 2020 and among MSM from 9.0% to 12.1%. Syphilis positivity among MSM fluctuated between 2.0% and 2.9% in 2011-2020. Positivity peaked (6.7%) during lockdown, while the number of diagnoses was similar to pre-lockdown. In contrast, HIV positivity continued to decrease from 2,0% to 0,3% among MSM in 2011-2020. Conclusion Prioritising persons at highest risk caused decreases in diagnoses, especially chlamydia and gonorrhoea, but increases in positivity. More information is needed to understand transmission dynamics, including testing at GPs, self-testing and sexual behaviour during coronavirus pandemic.
doi:10.1136/sextrans-2021-sti.338 fatcat:ujmp4oejr5amphra3dtpczs3ze