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Anti-inflammatory and immunosuppressive drugs and reproduction [article]

Yehuda Shoenfeld, Rolando Cimaz, Angela Tincani, Ann Parke, Roger A Levy, Raj Rai, Guillermo Ruiz-Irastorza, Ware Branch, Howard Carp, Ronald Derksen, Pierluigi Meroni, Sara De Carolis (+17 others)
2006

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Rheumatic diseases in women of childbearing years may necessitate drug treatment during a pregnancy, to control maternal disease activity and to ensure a successful pregnancy outcome. This survey is based on a consensus workshop of international experts discussing effects of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation. In addition, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs
more » ... y are discussed where data were available. Recommendations for drug treatment during pregnancy and lactation are given. 6-MP = 6-mercaptopurine; AAP = American Academy of Pediatrics; CI = confidence interval; COX = cyclo-oxygenase; CQ = chloroquine; CsA = cyclosporin A; CYC = cyclophosphamide; FDA = United States Food and Drug Administration; HCQ = hydroxychloroquine; IBD = inflammatory bowel disease; LDA = low-dose aspirin; MMF = mycophenolate mofetil; MTX = methotrexate; NSAID = non-steroidal anti-inflammatory drugs; OR = odds ratio; RR = relative risk; SLE = systemic lupus erythematosus; SSZ = sulphasalazine.
doi:10.7892/boris.19119 fatcat:x536thhvyvamlnjh7qu7z5grw4
Citation

Yehuda Shoenfeld, Rolando Cimaz, Angela Tincani, Ann Parke, Roger A Levy, Raj Rai, Guillermo Ruiz-Irastorza, Ware Branch, Howard Carp, Ronald Derksen, Pierluigi Meroni, Sara De Carolis, Andrea Doria, Michael Lockshin, Monika Østensen, Maurizio Clementi, Guido Valesini, Michelle Petri, Caroline Gordon, Ricard Cervera, Arsenio Spinillo, Antonio Brucato, Deborah Friedman, Jean Charles Piette, Andrew Czeizel, Munther Khamashta, Mario Motta, David Faden, Irene Cetin. "Anti-inflammatory and immunosuppressive drugs and reproduction." (2006)