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Prevalence of HLA DQB1*0602 allele in patients with migraine
2007
Arquivos de Neuro-Psiquiatria
BACKGROUND: Studies have shown a high prevalence of migraine among narcoleptic patients. HLA-DQB1*0602 and HLA DRB1 alleles are closely associated with narcolepsy. An increase in the HLA-DRB1 allele frequency in patients with visual aura has raised greater awareness of the genetic background in migraine. PURPOSE: Since the regions DR and DQ of the HLA are in tightly linkage desiquilibrium we hypothesize that HLA-DQB1*0602 might be associated to the pathophysiology of migraine. METHOD: We
doi:10.1590/s0004-282x2007000700005
pmid:18345414
fatcat:wgqmn726bjg2ln35bulwgcxe2a