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A single starfish Aurora kinase performs the combined functions of Aurora-A and Aurora-B in human cells
Journal of Cell Science
Aurora, an essential mitotic kinase, is highly conserved during evolution. Most vertebrates have at least two Aurora kinases, Aurora-A and Aurora-B, which have distinct functions in the centrosome-spindle and inner centromere-midbody, respectively. However, some non-vertebrate deuterostomes have only a single Aurora. It remains to be verified whether the single Aurora performs the same functions as vertebrate Auroras A and B combined. We have isolated a cDNA of a single Aurora (ApAurora) fromdoi:10.1242/jcs.076315 pmid:21048162 fatcat:6en42vyewjc4rggornkokri5gy