Gastric polyps are gastric lesions with a relatively low prevalence that are mostly asymptomatic and detected incidentally by endoscopy. Since some polyps are associated with Helicobacter pylori infection and can be a precursor to future malignancies, this research carries out a clinicopathological study of gastric polyps in hospitals in Yazd, Iran. Materials and Methods: The records of all the patients who had undergone endoscopy from 2011 to 2016 and had pathology reports of gastric polyps

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... e extracted from the archives of the hospitals' pathology departments and their demographic details, including age, gender, the anatomic site of polyp, clinical symptoms, Helicobacter pylori infection and the histopathology of the polyp were examined and recorded in a pre-developed checklist. The data obtained were analyzed in SPSS-17 at the significance level of P<0.05. Results: Of the 72 patients studied, 25 (34.7%) were male and 47 (65.3%) were female. Polyps were mostly prevalent in the over-60 age group (n=33, 45.8%). The most common anatomic site of the extracted polyps was the body of the stomach (n=38, 52.8%). Abdominal pain was the most frequent clinical complaint in the patients (n=37, 51.4%), and hyperplastic polyps were also the most frequent type of polyps observed (n=46, 63.9%). Most of the polyps had no concomitant pathologies (n=41, 56.9%). Only in 12 cases H. pylori infection was observed, nine of whom happened to be female. H. pylori infection was observed mostly in the age group of 45-60. No significant correlation was found between gender and H. Pylori infection in gastric polyps. Conclusion: In line with the results of previous studies on the subject, the incidence of polyps increases with age, and since most polyps are hyperplastic, their malignancy is not very likely. Nonetheless, people with idiopathic abdominal pain should be examined for gastric polyps.