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Failure to Detect Human Papillomavirus DNA in Malignant Epithelial Neoplasms of Conjunctiva by Polymerase Chain Reaction
American Journal of Clinical Pathology
A b s t r a c t To elucidate the putative role of human papillomavirus (HPV) infection in the etiology of conjunctival tumors, 44 formalin-fixed, paraffinembedded specimens of conjunctival tumors (24 patients with papillomas and 20 patients with dysplastic and/or malignant tumors) were screened for HPV infection using 4 different polymerase chain reactions (PCRs). Of the 24 samples of papilloma, 14 (58%) displayed positive results by applying nested PCR using primer sets of HPV consensus L1doi:10.1309/rvup-qmu3-5x6w-3cq1 pmid:11888082 fatcat:bljyxibabvfopmn23zco7nun74