Because of the vehemence of market competence, the individuation and diversification of consumer's demands and the complexity of products, the virtual prototyping technology for complex product becomes one of studying and applying hotspots in current simulation technology. The paper proposes a novel organization structure of multi-agent system for virtual prototype engineering, thus to support the life-cycle collaboration roundly and effectively. Then the paper discusses the four types of

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... -information agents, service agents, platform agents and application agents in detail. And the paper illustrates the relations among types of agents. At last, it proposes two key techniques of MAS: the internal structure of agent and agent communication language. All these prove that MAS is effectively and extendable when applying to virtual prototype engineering.