EVALUATION OF CORONARY RISK FACTORS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
English

Santosh R G, Rangaswamy R
2015 Journal of Evolution of Medical and Dental Sciences  
INTRODUCTION: Cardiovascular disease is the commonest cause of death globally. Acute myocardial infarction generally occurs when coronary blood flow decreases abruptly after thrombotic occlusion of a coronary artery causing focal or massive necrosis of cardiac muscle. The risk factor concept implies that a person with one risk factor is more likely to develop clinical atherosclerotic event and is more likely to do so earlier than a person with no risk factors. The presence of multiple risk
more » ... multiple risk factors further accelerates the atherosclerosis. Hence it is important to identify the major risk factors of coronary atherosclerosis in an individual with acute myocardial infarction so that further preventive measures can be taken in the form of lifestyle modification and pharmacotherapy. MATERIALS AND METHODOLOGY: This is a hospital based study. This study comprises of 100 cases of acute myocardial infarction admitted in ICCU under the department of medicine and 100 normal healthy controls in the age group of 29-85 years. Patients with the evidence of acute MI were diagnosed according to WHO criteria. Blood samples collected in vacutainers were analyzed for different biochemical parameters in the clinical biochemistry laboratory. RESULTS: Common risk factors have been evaluated in our study and we found that maximum MI patients were recorded in the age group of 51-60 years, with respect to other risk factors history like sex, majority of patients were males (82%), Sedentary life style (44%), Mixed dietary habits (84%), Family history of IHD (6%), Dyslipidemia and Smoking (46%), Hypertension (31%), Diabetes (37%), Obesity (18%). In our study we found that 81% of the patients of acute MI had multiple risk factors. CONCLUSION: Thus from the study we can conclude that risk factors play a major role in the genesis of coronary heart disease. Modification of these factors by pharmacotherapy, diet, physical exercises and behavioral therapy can improve the prognosis in these patients and also helps in reduction of incidence of CHD. KEYWORDS: Acute MI (acute myocardial infarction), IHD (ischemic heart disease), CHD (coronary heart disease), Diabetes mellitus, Hypertension. INTRODUCTION: Cardiovascular disease is the commonest cause of death globally. Acute myocardial infarction generally occurs when coronary blood flow decreases abruptly after thrombotic occlusion of a coronary artery causing focal or massive necrosis of cardiac muscle. The risk factor concept implies that a person with one risk factor is more likely to develop clinical atherosclerotic event and is more likely to do so earlier than a person with no risk factors. The presence of multiple risk factors further accelerates the atherosclerosis. Hence it is important to identify the major risk factors of coronary atherosclerosis in an individual with acute myocardial infarction so that further preventive measures can be taken in the form of lifestyle modification and pharmacotherapy. Atherosclerosis is a focal intimal disease of arteries ranging in size from aorta down to those of approximately 3mm diameter. The most commonly involved are aorta, coronaries, carotids, cerebral and femoral arteries. Branch points, curvatures, the sites of blood turbulence favour the development of atherosclerotic lesions.
doi:10.14260/jemds/2015/555 fatcat:o3zpqeebkncgzhz5ucjjuxcq6e