Memorability of photographs in subjective cognitive decline and mild cognitive impairment: implications for cognitive assessment [article]

Wilma A. Bainbridge, David Berron, Hartmut Schütze, Arturo Cardenas-Blanco, Coraline Metzger, Laura Dobisch, Daniel Bittner, Wenzel Glanz, Annika Spottke, Janna Rudolph, Frederic Brosseron, Katharina Buerger (+22 others)
2019 biorxiv/medrxiv   pre-print
INTRODUCTION: Impaired long-term memory is a defining feature of Mild Cognitive Impairment (MCI). We tested whether this impairment is item-specific, limited to some memoranda whereas some remain consistently memorable. METHODS: We conducted item-based analyses of long-term visual recognition memory. 394 participants (healthy controls (HC), Subjective Cognitive Decline (SCD), and MCI) in the multicentric DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE) were tested with images
more » ... from a pool of 835 photographs. RESULTS: We observed consistent memorability for images in HCs, SCDs, and MCI, predictable by a neural network trained on another healthy sample. Looking at memorability differences between groups, we identified images that could successfully categorize group membership with higher success and a substantial image reduction than the original image set. DISCUSSION: Individuals with SCD and MCI show consistent memorability for specific items, while other items show significant diagnosticity. Certain stimulus features could optimize diagnostic assessment, while others could support memory.
doi:10.1101/660365 fatcat:whry6zdvtvbhbbl235ociwcume