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The Effect of pH and Ionic Strength on Rate of Reaction of Plasma Albumin with Formaldehyde in Water Solution and Ethanol-Water Binary Mixtures
International Journal of Research in Chemistry and Environment
The effects of pH and ionic strength on the rate of reaction of plasma albumin with formaldehyde in water and 15%ethanol-water system were investigated in the pH range of 5.3-8.7 and neutral salt range 0.1-0.9 moldm-3 NaCl. The rate constants for the reaction in water medium have been found to increased with increase in pH. This has been observed to be similar with an analogous aldehyde, glutaraldehyde whose reactions with proteins increased with in increase in pH This behaviour is reported tofatcat:mcac7m6b7ze37oa2uf4k57llve