Digital angiographic assessment of the physiological changes to the regional microcirculation induced by successful coronary angioplasty

H Schühlen, N L Eigler, A M Zeiher, M M Rombach, J S Whiting
1994 Circulation  
after PTCA (P<.01). A comparison of T.i",' with stenosis flow reserve revealed a nonlinear relation. In 16 patients undergoing PTCA of the left anterior descending or circumflex artery, contrast injections into the left main stem allowed simultaneous measurements of Tmiij"in the adjacent, nonstenotic artery. Adjacent artery Ti",'j did not change after PTCA (25.8+6.2 compared with 25.6+6.8 min' before PTCA; P=NS); moreover, Ti"jcr'of the dilated artery measured after PTCA was equivalent to the
more » ... nstenotic adjacent artery, indicating normalization of microcirculatory responses. Conclusions These data suggest that Tmi,o'1 determined by digital angiographic impulse response analysis of a single contrast injection under resting flow conditions may be a practical method to assess the regional microcirculatory response to changes in stenosis severity effected by coronary angioplasty. (Circulation. 1994;90:163-171.) Key Words * digital angiography * myocardial perfusion a percutaneous transluminal coronary angioplasty by guest on
doi:10.1161/01.cir.90.1.163 pmid:8025992 fatcat:eau3traswfhwjeefrwkmg7g6vi