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Molecular Mechanisms Underlying Adhesion and Regulation of Virulence of Human Enterotoxigenic Escherichia coli
2018
Enterotoxigenic Escherichia coli (ETEC) is the key etiological agent of traveller's diarrhea. It accounts for 200 million cases of diarrhea and 380,000 deaths annually. ETEC uses proteinaceous appendages called pili in order to attach with host intestine, followed by secretion of enterotoxins leading to profuse diarrhea. Among various ETEC pili that are characterised till date, CFA/I is the archetype of a class of pili called class 5 (α pili) pili. CFA/I is composed of two types of protein
doi:10.25904/1912/976
fatcat:ya5kkvocmfaqtkmxspstv42d5a