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The effect of developmental pleiotropy on the evolution of immune genes in Drosophila melanogaster
[article]
2021
bioRxiv
pre-print
The pressure to survive relentless pathogen exposure explains the frequent observation that immune genes are among the fastest-evolving ones in the genomes of many taxa, but an intriguing proportion of immune genes also appear to be under purifying selection. Though variance in evolutionary signatures of immune genes is often attributed to differences in gene-specific interactions with microbes, this explanation neglects the possibility that immune genes pleiotropically participate in other
doi:10.1101/2021.05.12.443901
fatcat:lnunophr5beg5oclsk5mtaamrq