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NADPH Oxidases as Regulators of Tumor Angiogenesis: Current and Emerging Concepts
2012
Antioxidants and Redox Signaling
Stavros (2012) NADPH oxidases as regulators of tumor angiogenesis : current and emerging concepts. ABSTRACT Significance: Reactive oxygen species (ROS) such as superoxide, hydrogen peroxide and peroxynitrite are generated ubiquitously by all mammalian cells and have been understood for many decades to inflict cell damage and to cause cancer by oxidation and nitration of macromolecules including DNA, RNA, proteins and lipids. Recent advances: A current concept suggests that ROS can also promote
doi:10.1089/ars.2011.4489
pmid:22229841
fatcat:wp3v66lwtfe2pkrb6tyevegbwm