Objective: To evaluate the efficacy of a program of lifestyle change through psychological intervention, combined with pharmacological therapy, for coronary risk reduction in uncontrolled hypertensive patients with overweight and dyslipidemia over 11 months of follow-up. Methods: A randomized controlled trial with 74 patients assigned to three different treatment programs. One group (CT) only received conventional pharmacological treatment. Another group (OG) received pharmacological treatment

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... nd participated in a guidance program to control cardiovascular risk factors. A third group (LSPI) received pharmacological treatment and participated in a brief psychological intervention program for reduction of stress levels and changing of eating behavior. The main measure was the Framingham risk index. Results: CT patients presented an average reduction of 18% (p = 0.001) in coronary risk; OG patients elevated the risk by 0.8% (NS) and the LSPI group showed an average reduction of 27% on the Framingham risk index (p = 0.001). Conclusion: Pharmacological treatment combined with psychological intervention for reduction of stress level and changing of eating behavior resulted in additional benefits in coronary risk reduction. (Arq Bras Cardiol 2007;88(6):624-628) Pugliese et al Lifestyle change psychological intervention in coronary risk reduction Arq Bras Cardiol 2007; 89(4) : 203-208