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Correlation between histological grade and c-erbB2 oncoprotein overexpression in infiltrating ductal carcinoma of breast
The Malaysian journal of pathology
One hundred and twelve infiltrating ductal carcinoma of breast were studied by the standard avidinbiotin complex immunoperoxidase method on formalin-fixed, paraffin-embedded tissue sections, using a monoclonal antibody to c-erbB-2 oncoprotein. The same tumours were assessed and scored according to the Bloom and Richardson criteria into three histological grades. The distribution of tumours according to grade were: 8 Grade I, 34 Grade II and 70 Grade III. Forty-three (38.4%) tumours showedpmid:10879240 fatcat:4nbx7czupzch7cu37c3jguupga