PV-0424: Cyclin D1 silencing radiosensitises prostate cancer cells by impairing DNA-DSBs repair pathways

F. Marampon, G. Gravina, C. Festuccia, A. Colapietro, E. Di Cesare, E. Tombolini
2016 Radiotherapy and Oncology  
S198 ESTRO 35 2016 _____________________________________________________________________________________________________ perform the selection procedure for a set of patients. Subsequently, the choices are discussed in the group of observers and a set of selection rules is composed. In this lecture we will discuss the plan selection strategy for rectum cancer and its introduction in the clinic. Poster Viewing : 9: Radiobiology PV-0424 Cyclin D1 silencing radiosensitises prostate cancer cells by
more » ... impairing DNA-DSBs repair pathways. Purpose or Objective: Patients with hormone-resistant prostate cancer (PCa) have higher biochemical failure rates after radiation therapy. Cyclin D1 deregulated expression in PCa is associated with a more aggressive disease however its role in radioresistance has not been determined.
doi:10.1016/s0167-8140(16)31673-5 fatcat:izw5aktqnzbjrjqdshlhyjvhoq